Access numpy from dataframe

import pandas as pd
from io import StringIO
import sys

csv_data = \
'''A,B,C,D
1.0,2.0,3.0,4.0
5.0,6.0,,8.0
10.0,11.0,12.0,'''

df = pd.read_csv(StringIO(csv_data))
df
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df.values
array([[ 1.,  2.,  3.,  4.],
       [ 5.,  6., nan,  8.],
       [10., 11., 12., nan]])